Christian Lealiifano returns to the starting line up at inside centre while Pat McCabe moves back to the bench, while Tom Staniforth drops out of the match day 23.
On the bench, new recruit Tom McVerry will get his first opportunity in a Brumbies jersey having joined the club as flanker cover after a season ending injury to David Pocock.
Returning from a bye and a win over the Reds 14 days ago, the rest of the Brumbies team remains untouched.
Director of Rugby Laurie Fisher said the Chiefs presented a significant challenge.
“The line-out is an area we try to target every week, with a team like the Chiefs that’s also important, they tend to go short so we need to be aware of that,” Fisher said.
“That’s the line-out which has won the competition for the last two years and they always seem to find a way around the park.
“We haven’t played the Chiefs over for the last two years, we’ve played them twice away and been desperately close both times. I think being at home will present us with new opportunities.
“I think Anzac Day is a wonderful occasion in Australia these days, the new generation coming through have shown a great deal respect for the Anzac tradition and I believe it’s one of the finest days on the Australian calendar.”
Friday is the first time the Brumbies have faced a New Zealand side on Anzac Day in Australia and the third Kiwi team the Brumbies had played against in 2014.
1. Scott Sio , 2. Stephen Moore , 3. Ben Alexander , 4. Scott Fardy , 5. Sam Carter , 6. Jordan Smiler , 7. Jarrad Butler , 8. Ben Mowen (c) , 9. Nic White , 10. Matt Toomua , 11. Robbie Coleman , 12. Christian Lealiifano , 13. Tevita Kuridrani , 14. Joe Tomane , 15. Jesse Mogg
Replacements: 16. Siliva Siliva , 17. Ruan Smith , 18. JP Smith , 19. Jack Whetton , 20. Tom McVerry , 21. Michael Dowsett , 22. Andrew Smith , 23. Pat McCabe