Lions head coach Johan Ackermann has named Elton Jantjies to start at flyhalf against Super Rugby Champions the Chiefs in Hamilton with Marnitz Boshoff on the replacements bench.
Ackermann has made one change to the forward pack that lost to the Stormers before their bye a fortnight ago.
Warren Whiteley has made a full recovery from injury and will start at eighthman and will captain the side.
Meanwhile, in the backline, Faf de Klerk has reclaimed his spot in the starting XV. Elton Jantjies will start at flyhalf and Deon van Rensburg will return in the wing position, having recovered from his minor injury.
On the bench, Armand van der Merwe looks set to make his Vodacom Super Rugby debut should he get a run on Saturday.
Jacques van Rooyen will also provide cover off the wood, having been called up from the Vodacom Cup squad.
Due to De Klerk and Jantjies earning starting positions, Ross Cronje and Marnitz Boshoff are the other changes to the substitutions list.
15. Chrysander Botha ,14. Deon van Rensburg ,13. Lionel Mapoe,12. Stefan Watermeyer,11. Courtnall Skosan ,10. Elton Jantjies,9. Faf de Klerk ,8. Warren Whiteley (c),7. Derick Minnie ,6. Jaco Kriel,5. Franco Mostert ,4. Martin Muller,3. Julian Redelinghuys,2. Robbie Coetzee,1. Schalk van der Merwe
Replacements : 16. Armand van der Merwe,17. Jacques van Rooyen ,18. Ruan Dreyer,19. MB Lusaseni ,20. Willie Britz,21. Ross Cronje,22. Marnitz Boshoff,23. JW Jonker