Rory Duncan made one change to his side who play in the playoffs against Scarlets.
Johan Goosen will start with Niel Marais going to inside centre and Clinton Swart dropping to the bench.
The rest of the match-day squad is unchanged.
The winner of the game will face the Glasgow Warriors in the semi-finals.
Cheetahs – 15 Clayton Blommetjies, 14 William Small-Smith, 13 Francois Venter (c), 12 Niel Marais, 11 Sibahle Maxwane, 10 Johan Goosen, 9 Tian Meyer, 8 Uzair Cassiem, 7 Oupa Mohoje, 6 Paul Schoeman, 5 Reniel Hugo, 4 Carl Wegner, 3 Johan Coetzee, 2 Torsten van Jaarsveld, 1 Ox Nche.
Replacements: 16 Jacques du Toit, 17 Charles Marais, 18 Tom Botha, 19 Rynier Bernardo, 20 Henco Venter, 21 Zee Mkhabela, 22 Clinton Swart 23 Lloyd Greeff.