Ireland arrive in Cardiff to face Wales knowing that a win would take them top of the Six Nations, putting the pressure on England.
Currently three points behind Eddie Jones’ side with two games to play, Ireland know a loss could see England seal the title on Saturday.
An in-form Scotland may still have something to say about though and the neutral will hope the Championship does go down to its final round. Indeed, Vern Cotter’s men could still lift the silverware if Wales beat Ireland and they win at Twickenham before beating Italy next week.
For Wales the prospects are far more bleak after a dismal campaign that has seen them win one and lose two of their matches to date. After this tough game against Ireland at the Principality Stadium, they conclude their tournament with another difficult assignment in France.
The bookmakers have them slight underdogs on Friday and one would expect something similar in Paris next week, which begs the question will Wales finish with just one win to their name on the back of four straight defeats? If so, the pressure would be immense on Rob Howley.
2016: 16-16 draw in Dublin
2015: Wales won 16-10 in Dublin
2015: Ireland won 35-21 in Cardiff
2015: Wales won 23-16 in Cardiff
2014: Ireland won 26-3 in Dublin
2013: Ireland won 30-22 in Cardiff
2012: Wales won 23-21 in Dublin
2011: Wales won 22-10 in Wellington
2011: Wales won 19-13 in Cardiff
2010: Ireland won 27-12 in Dublin
Wales: 15 Leigh Halfpenny, 14 George North, 13 Jonathan Davies, 12 Scott Williams, 11 Liam Williams, 10 Dan Biggar, 9 Rhys Webb, 8 Ross Moriarty, 7 Justin Tipuric, 6 Sam Warburton, 5 Alun Wyn Jones (c), 4 Jake Ball, 3 Tomas Francis, 2 Ken Owens, 1 Rob Evans
Replacements: 16 Scott Baldwin, 17 Nicky Smith, 18 Samson Lee, 19 Luke Charteris, 20 Taulupe Faletau, 21 Gareth Davies, 22 Sam Davies, 23 Jamie Roberts
Ireland: 15 Rob Kearney, 14 Keith Earls, 13 Garry Ringrose, 12 Robbie Henshaw, 11 Simon Zebo, 10 Johnny Sexton, 9 Conor Murray, 8 Jamie Heaslip, 7 Sean O’Brien, 6 CJ Stander, 5 Devin Toner, 4 Donnacha Ryan, 3 Tadhg Furlong, 2 Rory Best (c), 1 Jack McGrath
Replacements: 16 Niall Scannell, 17 Cian Healy, 18 John Ryan, 19 Iain Henderson, 20 Peter O’Mahony, 21 Kieran Marmion, 22 Paddy Jackson, 23 Tommy Bowe