With Johnny Sexton out due to injury, Ireland coach Andy Farrell has turned to Ross Byrne to take the number ten jumper for their clash with England this weekend.
He will partner with Gibson-Park for this weekend in what should be a massive clash at Twickenham
In the midfield Farrell picked Bundee Aki to replace injured Henshaw with Chris Farrell take the number thirteen jumper.
With Sexton out Ireland will have their 107th captain in James Ryan this weekend.
Ryan will partner with Quinn Roux in the second row with an unchanged front-row in Cian Healy, Ronan Kellerher and Andrew Porter.
It is also a welcome return for CJ Stander packing down at blindside with O’Mahony who will move to the openside and Doris taking the number eight jersey.
Ireland: 15 Hugo Keenan, 14 Keith Earls, 13 Chris Farrell, 12 Bundee Aki, 11 James Lowe, 10 Ross Byrne, 9 Jamison Gibson-Park, 8 Caelan Doris, 7 Peter O’Mahony, 6 CJ Stander, 5 James Ryan (c), 4 Quinn Roux, 3 Andrew Porter, 2 Ronan Kelleher, 1 Cian Healy
Replacements: 16 Rob Herring, 17 Ed Byrne, 18 Finlay Bealham, 19 Iain Henderson, 20 Will Connors, 21 Conor Murray, 22 Billy Burns, 23 Jacob Stockdale