The second match this weekend wil be an Australian derby when the Brumbies take on the Reds in Canberra.
For the Reds their can be up to five players making their debuts for the Reds. Harry Wilson will pack down at number-eight for the weekend.
The trio of Dane Zander, Seru Uru and Hunter Paisami could potentially make their Queensland debuts after being named on the bench.
Upfront the Reds will be happy to see JP Smith and Feao Fotuaika back from injury.
The backline have the same look as last week pre-season win over the Waratahs with Lucas earning his second start at 10. O’Conner will partner Petaia in the midfield which could be an exciting combination this season.
Wright will lead the team with other strong leaders in Rodda, Speight and Hegarty.
Loesio will get his first crack at the number 10 jumper this weekend for the Brumbies with NRL convert, Solomone Kata will also make his debut on Friday.
Harry Lloyd and young flyhalf, Bayley Kuenzle will make their Super Rugby debuts off the bench.
In the second row Douglas and Swain will partner up with Alaalatoa to lead the side in their first game of the season.
Prediction: Going on last year the Reds have been building for greater things but the brumbies has gone back to their old roots, Believe the Brumbies will edge the Reds at home by 3
BRUMBIES: Tom Banks, Solomone Kata, Tevita Kuridrani, Irae Simone, Tom Wright, Noah Lolesio, Joe Powell, Pete Samu, Tom Cusack, Rob Valetini, Murray Douglas, Darcy Swain, Allan Alaalatoa (c), Folau Fainga’a, Scott Sio
Replacements: Connal McInerney, Harry Lloyd, James Slipper, Caderyn Neville, Will Miller, Ryan Lonergan, Bayley Kuenzle, Andy Muirhead
REDS: Bryce Hegarty, Jock Campbell, Jordan Petaia, James O’Connor, Henry Speight, Isaac Lucas, Tate McDermott, Harry Wilson, Liam Wright (c), Angus Scott-Young, Lukhan Salakaia-Loto, Angus Blyth, Taniela Tupou, Brandon Paenga-Amosa, JP Smith
Replacements: Alex Mafi, Dane Zander, Feao Fotuaika, Izack Rodda, Seru Uru, Moses Sorovi, Hamish Stewart, Hunter Paisami