Wales have secured the Triple Crown already and are now gunning for the Six Nations trophy with two rounds of matches to go.
This weekend sees them traveling to Rome to face Italy who has still not been able to win a Six Nations test again this year.
Wales coach Wayne Pivac has challenged his players to put a full 80-minutes in and see them stay unbeaten in this years championship.
He has made two changes from the side that beat England two weeks ago with Cory Hill replacing Adam Beard to partner his captain in the second row.
The rest of the pack remains the same with
Gareth Davies will also start this week at nine alongside Dan Bigger taking the set of hardy who will miss the rest of the Six Nations due to a hamstring injury.
Davies and North will continue their partnership in the midfield with Adams, Rees-Zammit and Williams as the back three again.
On the bench Elliot Dee, Rhys Carre and Leon Brown will cover the front row.
Franco Smith has made six changes to his side for the weekend. Stephen Varney has recover from his injury and will take the nine jumper again this weekend.
We also have Mattia Bellini on the wing this weekend with Juan Ignacio Brex and Carlo Canna in the midfield.
In the pack Smith has gone for a new prop pairing in Danilo Fischetti and Giosuè Zilocchi who takes over from Andrea Lovotti and Marco Riccioni.
In the second row Smith has gone with Niccolo Cannone over Marco Lazzaroni for this clash with the Welsh.
One can really not see Italy upsetting Wales in this one but if Wales are going to underestimate the Italians they might just get a surprise.
Predictions: Easy one really, Wales by 20
Italy: 15 Jacopo Trulla, 14 Mattia Bellini, 13 Juan Ignacio Brex, 12 Carlo Canna, 11 Montanna Ioane, 10 Paolo Garbisi, 9 Stephen Varney, 8 Michele Lamaro, 7 Johan Meyer, 6 Sebastian Negri, 5 David Sisi, 4 Niccolo Cannone, 3 Giosuè Zilocchi, 2 Luca Bigi (c), 1 Danilo Fischetti
Replacements: 16 Oliviero Fabiani, 17 Andrea Lovotti, 18 Marco Riccioni, 19 Marco Lazzaroni, 20 Maxime Mbanda, 21 Marcello Violi, 22 Federico Mori, 23 Edoardo Padovani
Wales: 15. Liam Williams, 14. Louis Rees-Zammit, 13. George North, 12. Jonathan Davies, 11. Josh Adams, 10. Dan Biggar, 9. Gareth Davies, 8. Taulupe Faletau, 7. Justin Tipuric, 6. Josh Navidi , 5. Alun Wyn Jones (CAPT), 4. Cory Hill , 3. Tomas Francis, 2. Ken Owens, 1. Wyn Jones
Replacements: 16. Elliot Dee, 17. Rhys Carre, 18. Leon Brown, 19. Jake Ball, 20. Aaron Wainwright, 21. Lloyd Williams, 22. Callum Sheedy, 23. Uilisi Halaholo